The heresy of Nestorianism was dealt a major blow on October 25, 431 when the Council of Ephesus replaced Nestorius as the Bishop of Constantinople. Nestorius held the belief that Jesus Christ had two natures (divine and human) that existed separately instead of the theological understanding that Jesus was both God and man at the same time. This is a picture of a mosaic from a basilica in Lyon, France depicting the Council.